| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1ab32c0998436007a46ead00c803e81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7fd38ff393036b78f4fa402ddeeae2d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8dbc98ec9c14de726bb513f0182ad7e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_85dc9d0481ab16afc042ce67d04be504
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_02fa1cc7724476874d0865e1775d72a6 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-924
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01166
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01031
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2402
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-005 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-24 |
| filingDate |
2003-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b930e1383ee1f534e5f38f02f21b09c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74a022a9020d113bbb2c51ef22a28925
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f8bcebc9a764e4a2acded56b0ab11f5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6230412b8ad6ccaa012061d6c30975b |
| publicationDate |
2004-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2004048558-A2 |
| titleOfInvention |
Heparanase mediated cell adhesion and uses thereof |
| abstract |
The present invention relates to a nucleic acid construct comprising a polynucleotide sequence encoding a heparanase-derived polypeptide having cell-to-cell and cell-to-matrix adhesive properties and being devoid of heparanase catalytic activity. The invention further relates to expression vectors, and host cells expressing said adhesion promoting non-catalytic heparanase molecule and to the promotion of adhesion by using such non-catalytic heparanase. More particularly, the invention relates to the use of the adhesion promoting non-catalytic heparanase molecules for enhancing cell-to-cell and cell-to-matrix adhesion in a tissue sealant composition and in implantable medical devices. The invention further provides methods of treatment of adhesion-related pathologies. |
| priorityDate |
2002-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |