| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7cfc288bd52e9ea48f67a8c384b2ba16 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4747
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56988 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2003-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5acc211723b8ac6b42724da4c7cf843
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0f10b357506119972c7c1bf349dfdac |
| publicationDate |
2004-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2004045519-A2 |
| titleOfInvention |
Induction of apoptosis by hiv-1 infected monocytic cells |
| abstract |
The present invention generally relates to the treatment or inhibition of diseases associated with HIV-1 infection. In particular, the present invention identifies a protein, which is secreted by macrophages as a result of HIV infection. The secreted protein induces apoptosis in the neuronal cells, as well as T cells and B cell. The protein is specifically expressed in the neuronal tissue of HAD patients but not in the neuronal tissue of patients with non-HIV associated dementia. Methods and compositions for decreasing, inhibiting, or otherwise abrogating neuronal cell apoptosis that leads to HIV-1 associated dementia are described. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112362864-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2102370-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2102370-A2 |
| priorityDate |
2002-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |