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publicationDate 2004-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2004043497-A1
titleOfInvention Stabilzation of radiopharmceuticals labeled with 18-f
abstract An 18F isotope-labeled FDG radiopharmaceutical is stabilized against degradation in radiochemical purity due to radiolysis using selected amounts of ethyl alcohol that depend on the activity concentration of the 18F with due regard to limits set by various pharmacopoeia standards. Any of the well-know production methods for the FDG may be used and the ethyl alcohol added at several stages, preferably as part of the standard hydrolysis step. This particular radiopharmaceutical is used extensively in diagnostic imaging with a Positron Emission Tomography technique.
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