Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0214d76abf2f43de3f99e2d9fb6759ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba9c925a0a18d37ba6d55bb958cc1360 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1f0cfd82d10801343fe5e7b01225f585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_640b46b1e5f8f4fd261a794f6a00eaf4 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6851 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01J49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N24-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00 |
filingDate |
2003-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_205f61add81607c2711a1142ec01ca65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a54db198169295fac8c33d2ea81f9ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2c3cdfadf6efb0d66ce25b426b1df71 |
publicationDate |
2004-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2004042072-A9 |
titleOfInvention |
Quantitative analysis of protein isoforms using matrix-assisted laser desorption/ionization time of flight mass spectrometry |
abstract |
The present invention provides for methods of quantitating the amounts of proteins or peptides, including those that are closely related isoforms, using matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS). Measurement of protein concentrations in vivo has been extremely difficult and problematic, and protein concentrations have not been shown to correlate well with mRNA levels, the standard used in the past. The present invention overcomes the deficiencies of prior methodologies by taking advantage of MALDI-TOF-MS technology and applying it to proteins and peptides in a way that allows for accurate, quantitative measurement in vivo of protein or peptide concentrations. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7160242-B2 |
priorityDate |
2002-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |