abstract |
It is intended to provide a medicinal preparation for transferring a chemotherapeutic (preferably an anticancer agent) into cells or the living body by using a virus envelope vector. Namely, a medicinal preparation containing a virus envelope vector having a chemotherapeutic encapsulated therein as the active ingredient. Examples of the anticancer agent include bleomycins, anthraquinone carcinostatic agents, mitomycins, actinomycins, taxane derivatives, camptothecins, cisplatins, staurosporines, vincristine, streptozotocin, 5-fluorouracil (5-FU) and its derivatives, pirarubicin, dolastatin and pharmacologically acceptable salts thereof. Examples of the virus include sendai virus, retro virus, adenovirus, adeno-associated virus, herpes virus, vaccinia virus, pox virus, influenza virus and so on. |