abstract |
Drugs having inhibitory activity against hematopoietic prostaglandin D2 synthase, containing as the active ingredient compounds represented by the general formula (I) or salts thereof: (I) wherein X is -N=C(R5)- or -NH-CH(R5)-; R1, R2, R3, and R4 are each hydrogen, halogeno, C1-6 alkyl, or hydroxyl; R5 is C1-6 alkyl or C6-10 aryl; and R is amino. |