Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_51d028c578ae85cb937b5b34a5129fbc |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-924 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54373 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2003-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_292fb714a1a660d07c38f678a5605eab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b893b188e4c24ff5bf4416abbae3d24d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30d783ab28b1112dfc90a26cebd7bbd7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c81eb880b4de8f71b7d89579aaedb97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfa30c80eab4d381875ef6fde2e706b1 |
publicationDate |
2004-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2004029625-A2 |
titleOfInvention |
Detecting molecular binding by monitoring feedback controlled cantilever deflections |
abstract |
The present methods and apparatus concern the detection and/or identification of target analytes using probe molecules. In various embodiments of the invention, the probes or analytes are attached to one or more cantilevers. Binding of a probe to an analyte results in deflection of the cantilever, detected by a detection unit. A counterbalancing force may be applied to restore the cantilever to its original position. The counterbalancing force may be magnetic, electrical or radiative. The detection unit and the mechanism generating the counterbalancing force may be operably coupled to an information processing and control unit, such as a computer. The computer may regulate a feedback loop that maintains the cantilever in a fixed position by balancing the deflecting force and the counterbalancing force. The concentration of analytes in a sample may be determined from the magnitude of the counterbalancing force required to maintain the cantilever in a fixed position. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11754505-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10054531-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022018786-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11543839-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018115751-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7981666-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9551702-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2508358-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7790440-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020157364-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012160393-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-100458431-C http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2508358-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11209369-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022200438-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022200439-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-3060803-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2776702-A1 |
priorityDate |
2002-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |