abstract |
It is intended to provide a method of inhibiting a nonspecific interaction between molecules characterized in that, in a process of immobilizing molecules on the solid phase support and analyzing a specific interaction between these molecules with molecules specifically interacting the same, the hydrophobic nature of the solid phase surface on the solid phase support is controlled, in particular, a hydrophilic spacer is provided in the step of immobilizing the molecules on the solid phase support. According to this method, the nonspecific interaction between molecules can be inhibited and thus nonspecific adsorption on the solid phase can be lessened. |