http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004024869-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b8e71233d46c313ac971fc4f9e4aa4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4f6b482e14e97aaf93ee35b6ccc3daf9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6bbef6685885d5a435a144f79c450e10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_65bc544eb01fdcc222067e915daad626 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c28f8c48be638ab63b25ca17483fb6e9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4748 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate | 2003-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19d7f588e86540972635c29bb3db9174 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d194e40bfe69836400fce537de9591c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63a923bf914b0806f0721bc71cd8b415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9eeec75c5da9f8e0d674c1a4aa81080f |
| publicationDate | 2004-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2004024869-A2 |
| titleOfInvention | Cancer associated antigens, sga-56m and sga-56mv, and uses thereof |
| abstract | The present invention relates to nucleic and amino acid sequences of SGA-56M and variants thereof. An exemplary variant of SGA-56M is SGA-56Mv. SGA-56M and SGA-56Mv are differentially expressed in cancer tissues and transformed cell lines. In particular, these genes are expressed at elevated levels in breast cancer and lung cancer tissues and cell lines. The present invention is also directed to methods for diagnosing a cancer in a subject, determining the prognosis of a cancer patient, and/or monitoring the efficacy of a treatment regimen for a cancer patient. The present invention further provides methods for screening and identifying modulators (e.g., antagonists or agonists) of SGA-56M and/or SGA-56Mv expression and/or activity. Antagonists identified using the methods of the invention are useful for the treatment of cancer patients. Also encompassed by the present invention are compositions including nucleic and/or amino acid sequences of SGA-56M and SGA-56Mv or SGA-56M/SGA-56Mv modulators and a pharmaceutically acceptable carrier. Such compositions may be used to advantage to treat a subject with a cancer to ameliorate the symptoms of the cancer or reduce the cancer cell burden in the subject. These compositions may also be utilized to prevent or delay the onset of a cancer in a subject exhibiting a predisposition to developing a cancer. |
| priorityDate | 2002-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1085.