| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_727be11a00d32c7ec5b8290b7571ed21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3883b511a109fd95a565fa7086a052df
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01ade9d9ede090f83c9417dea2313eb3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a444c7784478fdf9f5544b76c9305624 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-57 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57 |
| filingDate |
2002-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1aa88abcd31a44835b0f571a1781af76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fd5c738248444aaa20130fa6651bc38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1b3ae3a3da4d38de1d81afbfc01d4ba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c0c8421d533d702e047c9c25aa559b9 |
| publicationDate |
2004-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2004021975-A2 |
| titleOfInvention |
An improved process for the synthesis of pharmacologically active (z/e)-guggulsterones |
| abstract |
The invention relates to an improved process for producing pharmacologically active synthetic stereoisomeric mixture of guggulsterones (4) in the three steps. The mixture of guggulsterones consists of Z-guggulsterone [4,17(20)-trans-pregnadiene-3,16-dione] and E-guggulsterone [4,17(20)-cis- pregnadiene-3,16-dione] and could be in any relative ratio. This improved process comprises (a) epoxidation of 16-dehydropregnanolone acetate (1) with hydrogen peroxide (b) reduction of the so obtained epoxide (2) with hydrazine hydrate and (c) oxidation of the diol (3). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004094450-A1 |
| priorityDate |
2002-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |