http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004020650-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_46b9ca510a7d67b5a1c4667e5367ed2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b98b4f6db4672b0fb161b26cfc89685 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P35-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-02 |
filingDate | 2003-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee8e12c8911653f0aae19d38229f9ebd |
publicationDate | 2004-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2004020650-A2 |
titleOfInvention | An enzymatic process for preparing beta-lactams |
abstract | An enzymatic process under kinetical control for preparing b-lactams, by coupling the 7-amino group of a cephalosporin nucleus with the carboxylic function of an acetic acid derivative consisting of a residue with p-electrons, a short spacer and a carboxylic function activated as methyl- or ethylester. The process comprises using a penicillin amidase or a-amino acid esterase as free enzyme or in any suitable immobilised form; applying at least 100 mmol/l cephalosporin nucleus as long as it is soluble, otherwise 50 - 100 % of its maximum solubility is charged, applying the acetic acid activated as ester in a 1 - 3 fold molar ratio, and adjusting the pH to 6.0 - 8.0 and the temperature to 0 - 30°C. |
priorityDate | 2002-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 280.