Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78587acbfc8d4c9e9ac3baa7021087d7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
filingDate |
2003-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c09dcbe8a3a18f44d02284bdf09a925 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77917a96024e31d08c9b8dfedda11fd9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_840185ec86866229d5110691df9c26f4 |
publicationDate |
2004-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2004018697-A2 |
titleOfInvention |
Protease resistant ti-growth hormone releasing hormone |
abstract |
One aspect of the current invention is a composition for a modified growth hormone releasing hormone ('GHRH') or functional biological equivalent thereof. Another aspect of the current invention includes a nucleic acid molecule that encodes the modified GHRH or functional biological equivalent. The modified GHRH can be defined as a biologically active polypeptide that was engineered to contain a distinct amino acid sequence while simultaneously having similar or improved biologically activity when compared to a wild-type GHRH ('wt-GHRH') polypeptide. Another aspect of the current invention includes a method for delivering the composition of this invention to a subject, wherein the modified GHRH increases the level of growth hormone ('GH') secretion in a subject. The preferred subject is a human or domesticated animal. Additionally, the modified GHRH composition is resistant to degradation when compared to the wt-GHRH. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1450605-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1450605-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7338656-B2 |
priorityDate |
2002-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |