| abstract |
The invention relates to biodegradable composition with prolonged release of biologically active compounds, where the composition contains at least one biologically active compound and a carrier, which is based on biodegradable oligoester having the number mean molecular weight Mn from 650 to 7500, the weight mean molecular weight Mw from 800 to 10000, and the glass transition temperature Tg -35 az 45 °C, and which is prepared by polycondensation reaction of polyhydric alcohol containing at least 3 hydroxy groups with at least one aliphatic α-hydroxy acid in molar ratio of polyhydric alcohol to aliphatic α-hydroxy acid of 0.5:99.5 to 12:88, wherein the central molecule of biodegradable oligoester is a polyhydric alcohol, to the hydroxy groups of which chains created from several molecules of at least one aliphatic α-hydroxy acid are bound by ester bonds. |