| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4eca42e0f00225c99ae10e29649d83a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_02fa1cc7724476874d0865e1775d72a6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f84747e8d08b1023763356d0e7d1db68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d62e9868aa2a1bed14753b44929c12d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6939e6c7170d8c462a16349dbfff3d63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7fd38ff393036b78f4fa402ddeeae2d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01166
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2402 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-24 |
| filingDate |
2003-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d7ceeaef5e30fa4a56e1d8215939b15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a64284358c8990f535f83fea07e861ae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7541c952749c453bf5d3e2fb4638df4f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_536647d55ec4c5c4509bce8a5c73de50 |
| publicationDate |
2004-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2004009129-A1 |
| titleOfInvention |
Method and compositions for treatment of bone disorders |
| abstract |
The present invention relates to methods and compositions for increasing bone density and mass, osteoblastic activity and/or osteogenesis. These methods are based on increasing the bone levels of heparanase and/or expression of heparanase in bone, so as to enhance bone biomechanical and hematopoietic supportive properties. The invention further provides for methods and uses of heparanase for increasing bone density, mass, osteoblastic activity and osteogenesis in a mammalian subject in need thereof. The methods and uses according to the invention are particularly applicable for the treatments of a subject suffering from a medical condition characterized by bone deficit, bone loss, reduced bone mass or bone fracture and for subjects in need of enhancing the integration and anchorage of endosseous implants. |
| priorityDate |
2002-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |