http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004008101-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10c8c1b8563bbd4a2d00ef121f9b39de http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af23ee0d4544e8ed129a9897b775b9c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_201002d392e2bbcb1e1eaf5a00a84261 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60d2134a44f2b4765a9a1a36828c1d8c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate | 2003-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79495b2e57ff2646d884cef440d653a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd1dbd52899aefc7dde26ce2829f485a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24f6a6589aa4082fe26766e268a1f883 |
| publicationDate | 2004-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2004008101-A3 |
| titleOfInvention | The use of isocyanate linkers to make hydrolyzable active agent biopolymer conjugates |
| abstract | The invention provides bioconjugates of the formula: (I) in which A is an active agent comprising an active hydroxy or amino functionality and B is a biopolymer comprising an active hydroxy or amino functionality, and X1 and X2 are independently N or O, and R is substituted alkyl or unsubstituted alkyl or unsubstituted or substituted heteroalkyl from 1 to about 30 atoms in length. The biopolymer may for instance be a transport protein or an antibody directed to a transport protein (e.g., a p97 protein or antibody thereto). The active agent may be a therapeutic agent such as a chemotherapeutic agent or an antineoplastic agent or an enzyme. The bioconjugates find therapeutic usages according to the therapeutic indications of the active agents. Methods of making the bioconjugates and bifunctional isocyanate cross linking reagents of use in making such bioconjugates are provided. |
| priorityDate | 2002-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.