| abstract |
The present invention relates to 3-guanidinocarbonyl-1-heteroaryl-indole derivatives of the formula (I) in which R1 to R5 and Ar have the meaning stated in the claims. The inventive compounds are suitable for example as antiarrhytmic medicaments with cardioprotective component for infarction prophylaxis and infarction treatment and for the treatment of angina pectoris. They also inhibit in a preventive manner the pathophysiological processes associated with the development of ischemia-induced damage, in particular in the triggering of ischemia-induced cardiac arrhytmias and of heart failure. |