| abstract |
A process for producing a peptide having at least one asparagine sugar chain, characterized by esterifying a hydroxy group of a hydroxylated resin with the carboxy group of an amino acid in which the amino nitrogen has been protected by a lipid-soluble protective group, eliminating the lipid-soluble protective group to form a free amino group, amidating the free amino group with the carboxy group of an amino acid in which the amino nitrogen has been protected by a lipid-soluble protective group or of the asparagine moiety of an asparagine sugar chain in which the amino nitrogen has been protected by a lipid-soluble protective group, eliminating the lipid-soluble protective group to form a free amino group, repeating the steps (3) and (4) one or more times, and cleaving the resin with an acid; and a sugar peptide capable of being obtained by the production process. |