| abstract |
A phenoxypyridine derivative which has a chemical structure represented by the following general formula (I) and has Na+/Ca2+ exchanger inhibitory activity selective for the reverse mode, or a pharmaceutically acceptable salt of the derivative; and a therapeutic agent for renal diseases or circulatory diseases which contains the derivative or salt as an active ingredient. (I) (In the formula, Ar is phenyl or thienyl; -A- is -NHCO-B- or -BNHCO-; -B- is a single bond or alkylene; Pyr is optionally substituted pyridyl; R1 and R2 are the same or different and each is lower alkyl optionally substituted by one or more halogen atoms, halogeno, or hydrogen; n is an integer of 0 to 4; and m is an integer of 0 to 3.) |