abstract |
An azlactone compound (2) is reacted with an amidine compound (3) to obtain a pyrimidine compoundn(1), which is useful as an intermediate for enzyme inhibitors (elastase inhibitor,nchymase inhibitor, etc.). (1) (2) (3) Pyrimidine compound (1) Azlactone compoundn(2) Amidine compound (3) (In the formulae, the symbols have the same meaningsnas in the description.) |