| abstract |
The present invention relates to novel compounds, compositions comprising saidncompounds, and uses thereof, said compounds having the formula (a). X is -CH 2 -,n-O- or -NR 9 -;R is a carbocyclic or heterocyclic ring;R 1 isna cysteine trap;R 2a , R 2a' , R 2b , and R 2b' areneach independently hydrogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy,nand mixtures thereof; or R 2a' and R 2b' can takenntogether to form a double bond; R 9 is hydrogen or a unit having the formulan-L 2 -R 10 ; L is the same as defined herein above; R 10 nis hydrogen; substituted or unsubstituted C 1 -C 6 linear;nbranched, or cyclic hydrocarbyl; substituted or unsubstituted aryl; substitutednor unsubstituted C 1 -C 9 heterocyclic; and substitutednor unsubstituted heteroaryl. |