| abstract |
The invention relates to novel substituted aryl and heteroaryl derivatives of general formula (I), in which A, Ar, n, X, Y1, Y2, Y3, Y4, R1, and R5 are defined as per claim 1, to their prodrugs, tautomers, stereoisomers, mixtures and salts, in particular their physiologically compatible salts comprising inorganic or organic acids or bases, which have valuable characteristics. The compounds of the aforementioned formula (I), in which R5 contains no cyano group, have in particular an antithrombotic and a selective factor Xa inhibiting action with generally improved compatibility. The compounds of the aforementioned formula (I), in which R5 contains a cyano group constitute valuable intermediate products for producing the antithrombotic compounds of general formula (I). |