| abstract |
Disclosed herein is a compound represented by Structural Formula (I). R1 is a substituted or unsubstituted aryl group or alkyl group; R2 is a substituted or unsubstituted aryl group or cycloalkyl group; Ar is a substituted or unsubstituted aryl group; X is a -CH2-, -O-, -S- or -CO-, m is an integer from zero to two; n is an integer from 0-2 when X is -O-, -S- and 1-2 when X is -CH2- or -CO-. Also disclosed are methods of inhibiting kallikrein activity or urokinase activity in subject in need of such inhibition by administering a compound represented by Structural Formula (I). |