http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03101449-A3
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c76ecadad74a1a35270b3e3a34d60f37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_875b590d69302482c9b84d73afa08008 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-10 |
filingDate | 2003-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_493757b14602d4e876be19f13507be7c |
publicationDate | 2004-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-03101449-A3 |
titleOfInvention | Process for the preparation of 3,3,4,4-tetrafluoropyrrolidine and derivatives thereof |
abstract | The present invention relates to a method of making novel dipeptidyl peptidase-IV ('DPP-IV') inhibitor compounds useful for treating, inter alia, diseases that are associated with proteins that are subject to processing by DPP-IV, such as Type 2 diabetes mellitus, metabolic syndrome (Syndrome X or insulin resistance syndrome), hyperglycemia, impaired glucose tolerance, glucosuria, metabolic acidosis, cataracts, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic cardiomyopathy, Type 1 diabetes, obesity, hypertension, hyperlipidemia, atherosclerosis, osteoporosis, osteopenia, frailty, bone loss, bone fracture, acute coronary syndrome, infertility due to polycystic ovary syndrome, short bowel syndrome and to prevent disease progression in Type 2 diabetes. The invention also relates to a method of making 3, 3, 4, 4-tetrafluoropyrrolidine, a starting material utilized in the afore-mentioned method for preparing DPP-IV compounds. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8906901-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8093236-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8324383-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102171175-B |
priorityDate | 2002-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.