http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03099107-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08c22eedd111a3d3cbe2bb325aff5e76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e72837de81999e7e72cb78d59d19e28 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-96486 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6887 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57438 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 |
| filingDate | 2003-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_466d73991483dfe768a16ec1a16b9a19 |
| publicationDate | 2003-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-03099107-A2 |
| titleOfInvention | Methods and kits for the detection of renal cell carcinoma in a biological fluid of a patient |
| abstract | The present invention relates to novel methods for detecting and evaluating urological cancers and in particular renal cell carcinoma (RCC). The methods of the present invention are based on the discovery that extracellular matrix proteins are absent or decreased in the urine of patients-with RCC and are diagnostic markers for the detection of RCC. Furthermore, the methods of the present invention are based on the discovery that metalloproteinases (MP) activity determined by extracellular matrix protein degradation is increased in patients with urological cancers and are diagnostic markers for the detection of these cancers. Diagnostic agents and methods for detecting the presence of RCC in biological samples such as urine are disclosed. A kit for detecting the extracellular matrix proteins, degradation fragments of extracellular matrix proteins, and activity of MPs are also disclosed. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1846576-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1846576-A2 |
| priorityDate | 2002-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 249.