| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_832cc7e0b4a5f58418998a837b49bdc8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7cbd96c8085de5fecfa51f868f489019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_70ebe392b4988c5479996055ae123c27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42c2455d6f886535463c227dbaedb887 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-11022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46 |
| filingDate |
2003-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_062c7148d20143a1f05bfb7555b3a146
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92e40ed5c733413e56a91741a56222e6 |
| publicationDate |
2003-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-03098220-A1 |
| titleOfInvention |
Modulation of mitosis by enhancing the interaction of cdc24a and cyclinb/cdk1 |
| abstract |
The invention generally relates to compositions and methods for modulating entry into mitosis. In one aspect, the invention provides methods for treating or preventing a hyperproliferative disorder in a mammal by promoting the phosphorylation of Cdc25A or the dephosphorylation of cyclin B/Cdk1, or by enhancing the activity of at least one molecular component of the Cdc25A and cyclin B/Cdk1 regulatory interaction/feedback pathway. In another aspect, the invention provides compositions capable of promoting the pathway. The invention has a wide range of important applications including providing screens for compounds that enhance the activity of one or more of the molecular components in the pathway and providing methods for screening a patient population. |
| priorityDate |
2002-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |