| abstract |
Fluorescent sensor compounds having the formula: (1) wherein L is selected from the group consisting of alkyl, alkylene, aryl, cycloalkyl, alkoxy, aryloxy, arylalkyl, and arylalkyloxyl; each m, m', n, n', p, and p' is independently an integer from 0 to 4, inclusive; and each R1, R'1, R2, R'2, R3 and R'3 is independently selected from the group consisting of hydrogen, alkyl, alkylene, aryl, cycloalkyll, alkoxy, aryloxy, arylalkyl, arylalkyloxyl, halo, substituted and unsubstituted amino, and substituted and unsubstituted thiol, are useful for the selective detection of saccharides such as glucose and sialyl Lewis X. The compounds find particular use in detecting saccharides in biological samples, and in detecting cancer cells that express cell surface polysaccharides such as sialyl Lewis X. |