http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03094903-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ecb094da95541fafc75021f569688cdc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec278f55741bfdd6fb9ab250e90b8085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e746b8f75061e5934fcea509fbf8dd8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7fdb0d3c79dc47aa9dd115cf6dc75789 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0fdbe4440ca9156090078a331a05d176 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
| filingDate | 2003-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_660cc348360ff22b3cde61d466897764 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7127bf896aff7640c249200c128e1acb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d961bf25c76164e0dc11be830d1d229c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1960b88b47b0688bfc82853f168d07d8 |
| publicationDate | 2003-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-03094903-A1 |
| titleOfInvention | A method of treatment |
| abstract | The present invention relates generally to a method for preventing, inhibiting or otherwise reducing cell death. More particularly, the present invention contemplates a method for preventing, inhibiting or otherwise reducing neuronal cell death such as during neurodegenerative disease or following trauma. The method of the present invention is generally practiced by the administration, to a mammalian including a human subject, of an effective amount of an agent which blocks, retards or otherwise impairs ions from entering or passing through an ion channel. In one particular embodiment, the ion channel is a potassium (K) ion (K+) channel. The present invention further provides compositions comprising ion channel blockers and in particular K+ channel blockers. The compositions may also comprise other therapeutic agents such as agents which reduce levels of, or the activity of, a neurotrophin receptor. The present invention further provides methods for promoting cell survival by promoting intracellular cleavage of the neutrophil receptor by generating or introducing intracellular forms of the receptor such as by genetic or protein supplementation means. The present invention further provides a method for determining the likelihood of neurological cell degeneration by determining the level of function of K+ channels wherein an impaired ion channel is indicative of a reduced likelihood of neuronal cell apoptosis. Furthermore, the present invention provides antagonists of K+ channels, such as antagonists of molecules which mediate K+ channel activation via neurotrophin receptors or domains thereof. |
| priorityDate | 2002-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1395.