abstract |
This method for producing phosphatidylethanolamine or lysophosphatidylethanolamine is characterized by the reaction of lecithin comprising at least one selected from the group consisting of phosphatidylcholine, phosphatidylethanolamine, phosphatidic acid and phosphatidylinositol in non-organic solvent system comprising calcium chloride and buffer. Therefore, the present invention eliminates the danger or difficulty in purification, which may exist in the case where toxic organic solvent is used and the present invention enables low inactivity of enzyme and high reaction efficiency. In particular, isolation and purification process after the completion of the reaction can be simplified and organic acid used in the isolation and purification process can be easily recovered since the present does not use organic solvent during the enzymatic reaction. Furthermore, even the lecithin having high purity can be dispersed smoothly in water. |