http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03089054-A2

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filingDate 2003-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8f4f78c6795b09279d8849012441906
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publicationDate 2003-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-03089054-A2
titleOfInvention Electrical stimulation for thrombolytic therapy
abstract An electrical stimulation apparatus is provided for delivering an electrical field or electrical current over a predetermined period of time to a vascular tissue in order to stimulate a cell initiated thrombolytic peptide response in cells within the vascular tissue. The electrical stimulation apparatus includes an electrical field or electrical current generating unit including a power supply, a control mechanism interconnected with the power supply, and a plurality of electrodes designed to generate an electrical field or electrical current proximal to, or within to the vascular tissue. The amplitude of the electrical field or electrical current delivered to or generated proximal to, or within the vascular tissue, and the duration of the period of delivery are sufficient to stimulate production of thrombolytic peptides in the vascular tissue. The control mechanism preferably includes a computer processing unit in electronic communication with the power supply, the computer being programmed to cause the electrical stimulation apparatus to deliver a predetermined amount of electricalcurrent or voltage over a predetermined period of delivery to the plurality of electrodes such that the plurality of electrodes are in contact or proximity with the vascular tissue.
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