| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1cec6e3b0d6f42d6aefef757ffc187a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6a8a497316c96dd7c248b049b12537be
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1d7aef3a2b873a893f467e217797255
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fb05d7e8cb2bd93d583c536b4d6b8912
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f85be07084a22a0d9a1f08ce9e0f7892
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61a1c9a6470c6d706fc3b896c0234e89 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70571 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
| filingDate |
2003-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ca80b85e4e8b095dc652be0abc95b08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7341caf562fcbd8f7e4ae59ae9fc60d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a63cde0df5a836379c450f3403da9d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc958ef7935bf19ed7fa86358bc0c6f4 |
| publicationDate |
2003-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-03087373-A2 |
| titleOfInvention |
Production of recombinant fragments of muscle acetylcholine receptor and their use for ex vivo immunoadsorption of anti-ach receptor antibodies from myasthenic patients |
| abstract |
A procedure which involves the production of extracellular domains (or larger parts including these domains) of human muscle acetylcholine receptor (AChR) expressed in heterologous or homologous systems and obtained in sufficiently folded state appropriate for binding major fractions of anti-AChR antibodies in myasthenia gravis (MG) patients and of immunoadsorbing these antibodies when said polypeptides are used as permanently immobilized on insoluble matrixes. This procedure allows the ex vivo selective elimination of the antibodies against human muscle acetylcholine receptor (AChR), as a replacement and improvement of the non-specific plasmapheresis or Ig apheresis, for the temporary repeated treatment of the disease MG. |
| priorityDate |
2002-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |