http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03085132-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff3e741d8c3082a79ba472a5a4c2bef8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9059fb91e79718057a75e72ddc8847b3 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2003-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25693568f660962b3eeb33b673559e34 |
publicationDate | 2003-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-03085132-A2 |
titleOfInvention | Method for analysis of methylated nucleic acids |
abstract | A method is disclosed providing analysis of the degree of methylation within nucleic acid samples, including the degree of methylation within CpG islands. After bisulfite treatment of a nucleic acid sample to convert cytosines to uracils, multiple species of paired oliogonucleotide primers and optionally a methylation insensitive reference primer pair are used to amplify target sequences within the sample by methylation specific PCR. Amplification of multiple primer pairs is combined with the use of a real time PCR. Amplificates of primer pairs are detected and quantified by comparison, thus allowing for a detailed, more specific, and quantifiable analysis of the methylation status within a complex CpG methylation pattern of a nucleic acid sample. Primer pairs and a kit are also disclosed. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005075671-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2481810-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006113770-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10731215-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009132315-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7820385-B2 |
priorityDate | 2002-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.