| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61e1bf9444df3c228b60ead1e1f62b8a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2003-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4320192eec4cbf7e3c04cf768662711d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e2824fa43f7aee9bdf5fc4cbbda21fe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14d055625d223c2cba1f3d0965c769ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fe7efc2f984a575876fe646c63de922 |
| publicationDate |
2003-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-03085083-A2 |
| titleOfInvention |
Liver necrosis predictive genes |
| abstract |
The invention provides toxicity predictive genes that can be used to predict toxicity in response to one more agents. The invention provides for a method of predicting the liver toxicity in an individual to an agent. The method comprises obtaining a biological sample from an individual treated with the agent. The expression of one or more liver toxicity predictive genes in the sample is measured, wherein the genes are selected from a group consisting of partial gene sequences of genes identified as responsive to agents causing liver necrosis. The process generates a test expression profile. The test expression profile is used with a set of reference expression profiles in a Predictive Model to determine whether the agent will induce liver toxicity in the individual. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7469185-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8048638-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10646555-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7426441-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7645584-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7415358-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006107846-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9682132-B2 |
| priorityDate |
2002-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |