| abstract |
There is provided a composition for modifying NAD production, the composition including an NMNAT modifying compound and a pharmaceutically acceptable carrier. Also provided is a cDNA sequence encoding NMNAT. A method of treating for example, diabetes, cancer, myocardial infarction, stroke, neurodegenerative disorders, shock, and aging by administering to the patient an effective amount of a composition for modifying NAD production is also provided. There is further provided a gene therapy including a sequence encoding NMNAT included therein and the method for incorporating the sequence effectively into a host genome. |