http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03078593-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f3aa96540fa59c8d420f9e9f8e02b96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_92c347ba2ea2d7e1f892a7c111bf3c48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff3e741d8c3082a79ba472a5a4c2bef8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 |
| filingDate | 2003-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f0c3bd2424e179a79bbe17d4a6c1855 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_975e5e6e5f664842f3aceaa329fec4bb |
| publicationDate | 2003-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-03078593-A2 |
| titleOfInvention | Discovery and diagnostic methods using 5-methylcytosine dna glycosylase |
| abstract | The present invention provides methods for identification of methylated, and/or potentially methylatable CpG dinucleotides in genomic DNA sequences, and methods for isolating genomic DNA sequences comprising methylated CpG dinucleotide sequences. The present invention further provides methods for comparison of the methylation status of specific CpG dinucleotides, and patterns thereof between normal and diseased genomic DNA sequences, along with methods for determining all potentially methylatable CpG dinucleotides in a genomic DNA sample. Specifically, the present invention discloses a novel use of 5-methylcytosine DNA glycosylase (5-MCDG) in combination with art-recognized DNA base excision repair (BER) enzymes, and in particular embodiments, in combination with DNA methyltransferase to specifically label methylated CpG dinucleotide sequences in genomic DNA sequences. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102005023055-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160050508-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101654004-B1 |
| priorityDate | 2002-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 470.