http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03077869-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27f0a01a91698d0dd55fd76ba1e5a90a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1ca2fe5a1e9022aa0323cbb48d30f5e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 |
| filingDate | 2003-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbb24255bc42a7fc9a1c0d311db79497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d00ea69d5a92714cd54152d2950c4e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfa9d650f507a0ada991cb5d84312d8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc25b397962fe8e95308b86ea99b5f23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_063fd282030cfc2d1f17c659b70a6b5b |
| publicationDate | 2004-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-03077869-A3 |
| titleOfInvention | Neuroprotective spirostenol pharmaceutical compositions |
| abstract | The present invention relates to methods, kits, combinations, and compositions for treating, preventing or reducing the risk of developing a disorder or disease related to, or the symptoms associated with, neurotoxicity in a subject, particularly to beta-amyloid-induced neurotoxicity and Alzheimer's disease. The compounds of the present invention are biologically active 22R-hydroxycholesterol derivatives containing a common spirost-5-en-3-ol structure. The invention further provides a method for treating a patient having a neurological disease or disorder such as global and focal ischemic and hemorrhagic stroke, head trauma, spinal cord injury, hypoxia-induced nerve cell damage, nerve cell damage caused by cardiac arrest or neonatal distress, epilepsy, anxiety, diabetes mellitus, multiple sclerosis, phantom limb pain, causalgia, neuralgias, herpes zoster, spinal cord lesions, hyper algesia, allodynia, Huntington's disease, and Parkinson's disease, by administering to the patient a therapeutically effective amount of 22R-hydroxycholesterol or a therapeutically active analog thereof. |
| priorityDate | 2002-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.