| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f11c07386864d8a4c8ea091d16ce67b6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8c0982b0f02b1ed6d20a315370a3a3a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9791dc672011e65a541164694b6156a2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f60f7884c3b8246b6939e7ca6e98d356
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c1c102f1bde6537b7f63fb6d3571e9e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8fc4f35f61eed1722857417a2ce971d9 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-19 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-88 |
| filingDate |
2003-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe3b7d387e355bd73a1feed02dc81eb2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_052184f5b494d4c2ab4121ebdb9d9be9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc4cd7f5a00e3c552d0c504b56cca2a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6066288c42ce116edd58981db39632b2 |
| publicationDate |
2004-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-03077868-A3 |
| titleOfInvention |
Synthesis of synthons for the manufacture of bioactive compounds |
| abstract |
The present invention is based on the discovery that 2-deoxyribose-5-phosphate aldolase (DERA, EC 4.1.2.4) and variants thereof can be used to catalyze sequential asymmetric aldol reactions between a wide variety of donor and acceptor aldehydes. The reaction products typically contain at least two new stereogenic centers and can be produced in enantiomerically pure form. As such, DERA catalyzed asymmetric aldol chemistry can be exploited to produce synthons for the synthesis of a variety of bioactive molecules. |
| priorityDate |
2002-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |