| abstract |
Compounds represented by the following general formula (I); a process for producing these compound by culturing a microorganism, which belongs to the genus Aspergillus and is capable of producing the compounds, and collecting the compounds from the culture medium; angiogenesis inhibitors comprising these compounds as the active ingredient; and an Aspergillus sp. F-1491 strain capable of producing these compounds: (I) wherein R represents methyl or ethyl; R1 represents hydrogen, chlorine, hydroxy or methoxy; and R2 represents hydroxy or R1 and R2 together form an epoxy ring structure. |