abstract |
The invention relates to a method for in vivo differentiation of monocytes in mature dendritic cells, wherein a) monocytes are provided in an appropriate culture medium, b) the monocytes are differentiated in dendritic cells in the presence of a differentiation factor, c) L- alpha -lysophosphatidylcholine is added to the medium and mature dendritric cells are obtained. The invention also relates to the use of at least one inhibitor of L- alpha -lysophosphatidylcholine in the production of a medicament for the prevention of an inflammation and/or in order to combat an inflammatory disease and/or autoimmune disease. |