| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b86c0f9ee64fe220cf2c58ebbebfd2e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fb42a25ff59e07509ca94febc459e653
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4eaa9fed7425f5711fbefc2fddb92b3c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10122 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-02 |
| filingDate |
2003-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_674baa054b194bfc7b7e31c80e409fcd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b90783ade65a1a1789700b8cb552d82 |
| publicationDate |
2003-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-03072731-A2 |
| titleOfInvention |
STABILIZED HBc CHIMER PARTICLES HAVING MENINGOCCOCAL IMMUNOGENS |
| abstract |
A chimeric, carboxy-terminal truncated hepatitis B virus nucleocapsid protein (HBc) is disclosed that contains an immunogen for inducing the production of antibodies to Meningococcal proteins. An immunogenic Meningococcal epitope is expressed between residues 76 and 85 of the HBc immunogenic loop sequence. The chimer preferably contains a Meningococcal-specific T cell epitope and includes a C-terminal cysteine residue for enhanced stability of self-assembled chimeric particles. Methods of making and using the chimers are also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10899795-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104220080-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104220080-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9637751-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10617748-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2013214700-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11226332-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11193114-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9555097-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11485768-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2724994-C2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10662232-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10982196-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11718650-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10729791-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11787849-B2 |
| priorityDate |
2002-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |