| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_35e0cdb2096a79592c1fcdd88643efa3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5d0873e9c8269793eabe838ceb1112a6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d99a3a0bbe29e9facad79005f43e0fa0 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate |
2003-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2af4b5f66adafa29089b28c95d4c271c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efae07c055fa91b795c214a86b656b36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70bfea9c98794f1669a830cca605a7db |
| publicationDate |
2003-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-03072042-A2 |
| titleOfInvention |
Malonate-claisen rearrangement for preparation of integrin receptor antagonist intermediates |
| abstract |
A novel process is provided for the preparation of chiral unsaturated ester intermediates useful in the asymmetric syntheses of α νβ 3 integrin receptor antagonists. The instant process involves an efficient Claisen rearrangement of a malonate ester of a chiral allylic alcohol precursor followed by hydrolysis and decarboxylation. The unsaturated ester intermediates can be converted in a 2-step sequence into the desired substituted nonanoic acid derivatives. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11426473-B2 |
| priorityDate |
2002-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |