Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ceec196ffebcf0034293bb9755dbc4e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c4a5691cd82b973cfa90657957103e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8345f4e46a360b98decf9f339ac67a2b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_341c79201f186c73ef26da1d69393e99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07c9542186133097bd6bbb7d92393090 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_04290e00b6fc9f7196f863a7dec7a362 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39489f8f8f00b89cc80397bf13dda4a8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-19 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
filingDate |
2003-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c27fec57df9e258110eb93ef85d94d2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fc0a780db0fadf8e0da49b85aa4f021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5ba65ae6f12560a64edd781ed85924d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_766dcea5d359a1730fe6cc72de10ad74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cec85f0aa964424067c243d3a279c123 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c3c5a5cf26e719873085fa3194f2028 |
publicationDate |
2003-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-03070880-A2 |
titleOfInvention |
Bacteria with reduced genome |
abstract |
The present invention provides a bacterium having a genome that is genetically engineered to be at least 2 to about 20% smaller than the genome of its native parent strain. A bacterium with a smaller genome can produce a commercial product more efficiently. The present invention also provides methods for deleting genes and other DNA sequences from a bacterial genome. The methods provide precise deletions and seldom introduces mutations to the genomic DNA sequences around the deletion sites. Thus, the methods can be used to generate a series of deletions in a bacterium without increasing the possibility of undesired homologous recombination within the genome. In addition, some of the methods provided by the present invention can also be used for replacing a region of a bacterial genome with a desired DNA sequence. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8039243-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010030986-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8043842-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8119365-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010030986-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2298912-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101379436-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013059595-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160128362-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1784489-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1784489-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010093708-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2423314-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007118162-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8765408-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005087940-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7303906-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011080505-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012501680-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102315246-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015073720-A1 |
priorityDate |
2002-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |