| abstract |
The present invention relates to the production of proteins and other substances of interest in the saliva of transgenic animals, in particular of mammals which produce large amounts of saliva, and more particularly of monogastric ruminants, of ovine, goat and bovine mammals. . Preferred embodiments of the invention relate in particular to the production of exotic and modified proteins in the saliva of these animals, including in particular a human fibrinogen, a human prothrombin and a human thrombin, among other things. The invention also relates to techniques, devices, genetic constructs and transgenic constructs for the production of proteins and other substances of interest. This invention finally relates to a new saliva and new compositions derived from saliva, to new products obtained from this saliva and to uses of this saliva, to compositions derived from saliva and to new products. |