| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e313d4e0b8d75004c7fde3bfb6eadaec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_52fbb113115ccf333ff649fd4b4efd21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75d35d845b4e05ab217158cd9facab7e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f3fd1afe3264d1076b11f3f63e282359
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ebf7a125e961249b92cefd1d5e024bdc |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C17-2635
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5352 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C2-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C5-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C17-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C15-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C1-34 |
| filingDate |
2003-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47421da3c0b45fbf68859f01b9a047b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_612476b86ba004d97d808f8b7ae5461a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1cdeabed88adafeea7a5cf256453bbb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d82ea4dcd6846d7518e68649296f4d9 |
| publicationDate |
2003-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-03066548-A2 |
| titleOfInvention |
Solvent-free mechanochemical preparation of phosphonium salts, phosphorus ylides, and olefins |
| abstract |
The present invention provides a method of preparing a phosphonium salt of the formula [R1R2R3P-CR4R5R6]X, comprising ball-milling a phosphine of the formula R1R2R3P with a compound of the formula XCR4R5R6; a method of preparing a phosphorus ylide of the formula R1R2R3P=CR4R5, comprising ball-milling a phosphonium salt of the formula [R1R2R3P-HCR4R5]X in the presence of a base; and a method of preparing an olefin of the formula R4R5C=CR7H or R4R5C=CR7RB, comprising ball-milling a phosphorus ylide of the formula R1R2R3P=CR4R5 with a compound of the formula R7C(O)H or R7C(O)R8. The inventive method produces phosphonium salts and phosphorus ylides by mechanical processing solid reagents under solvent-free conditions. The advantages of the present invention over conventional solution methods, include: (1) extremely high selectivity; (2) high yields; (3) low processing temperatures; (4) simple and scalable reactions using commercially available equipment; and (5) the complete elimination of solvents from the reaction. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023167321-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020009016-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2020009016-A1 |
| priorityDate |
2002-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |