Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1aa90debbf723d90161dc3f53a0458b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_22bf1527b15c85d1ea16c508c5014d9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8dba5e346b6a9829653572310284dcf3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e51e54f442004ec571fb31854617cbfa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05f1bd7044b804e915326b0250d42f1e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c9e604870a3723345b7eeecf4c85d83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ce2fc29e32510a5d7cb961c72d4b3c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa9fc68b0b5d70b33785b494a8b85452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3aaa64837267ab15b721667f401817fe |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6803 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate |
2003-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44066148c2474a1605017b84ebe33976 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e0881376ad827b4808cb2c47898858b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_090e6b5fa80a8f51e3e6a5eef74b9b01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_856ea543e12d3a80b121ec29475a9583 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ecd07d0bccdfc5d87569d20695a3880 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a2e27dee01baeb2d793c1392734388a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5bdf991f7e3a7833a24d98fb3647682 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a08986f3fdb885862bc1eb8bd1c4bde |
publicationDate |
2003-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-03064704-A1 |
titleOfInvention |
Chemical proteomics |
abstract |
The invention relates to methods and reagents for identifying/isolating protein targets of chemical compounds (for example, drug candidates) using mass spectrometry. The invention provides a method for capturing and identifying proteins using tethered small-molecule probes. This technology also allows the market expansion of known drugs by finding new therapeutic targets; identification of the mechanism of toxicity of drug candidates or drugs which failed in the clinic; identification of new chemical tools for chemically-driven target validation; identification of new drug leads; and identification of the mechanism of action of drugs and drug candidates. A key advantage of the technology is that a single experiment can identify the numerous proteins which interact with a probe (or 'bait'). |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004064972-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9034798-B2 |
priorityDate |
2002-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |