http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03061562-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d78f047fbb972816ba1996d330793292 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_364afb7d18bfc2c02872cae4c7d78f5a |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-005 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
filingDate | 2002-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1975acd3fa93899e2412f84abd989271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae5b36b64cb94da1a8e612c98a29ebe2 |
publicationDate | 2003-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-03061562-A2 |
titleOfInvention | Production of recombinant therapeutic bioscavengers against chemical and biological agents |
abstract | This invention relates to a method of producing recombinant biosensor molecules for use in therapy to provide protection against toxicity from exposure to toxins or drugs containing chemical / biological agents. This invention also relates to the production of glycoproteins which exhibit poor stability in vivo and are therefore inadequate in therapeutic treatments without the additional post-translational modifications of the expressed molecules. According to one embodiment, the method combines molecular and biochemical technologies, first in the expression of recombinant molecules and then in the glycoslyation in vitro of the expressed purified or partially purified molecules, intended to simulate the profiles of glycoproteins. native molecules. According to another embodiment, it is possible to obtain post-translational modifications by direct genetic modification of the cells used in the protein expression system. Although the invention is intended for use in vivo, it allows in vitro decontamination. Recombinant detoxifying agents can be used in many terrorist, therapeutic and environmental scenarios concerning the well-being of the military and civilians. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10106785-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2661492-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2661492-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2661492-B1 |
priorityDate | 2001-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 304.