| abstract |
Compounds represented by the general formula [I] or salts thereof, which are useful as lipid-rich plaque inhibitors and/or ACAT inhibitors: [I] wherein R1 and R2 are each hydrogen, halogeno, an optionally substituted linear hydrocarbon group, or hydroxyl which may be substituted with an optionally substituted linear hydrocarbon group, or R1 and R2 together with the carbon atoms adjacent thereto may form an optionally substituted carbocyle or a dihydrofuran ring which may have an oxo group; A is a benzene ring which may be further substituted; B is an aromatic ring which may be substituted; X is a free valency or a spacer whose main chain has 1 to 6 atoms; Y is carboxyl which may be esterified, carbamoyl which may be substituted, cyano, or an optionally substituted heterocyclic group bearing a hydrogen atom capable of causing deprotonation. |