| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_433bd708e3bef8c78524795351f6be36 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6803 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-483
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 |
| filingDate |
2002-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae7837e89e3ef93d5b98a5e9940fc59d |
| publicationDate |
2003-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-03056343-A2 |
| titleOfInvention |
Method for protein expression analysis |
| abstract |
The present invention is a method for analysis of at least peptides comprising extracting proteins from at least one set of cells; digesting the extracted proteins; derivatising the protein fragment mixture with an isotopically labelled reagent molecule; separating the protein fragment mixture by multi-dimensional chromatography; and analysing the protein fragment mixture by mass spectroscopy (MS) in parent ion or neutral loss scanning mode, thereby detecting or measuring the amounts of the labelled protein fragments. In a preferred embodiment, two sets of cells are combined in the method in order to compare the expression levels of two different states. Moreover, the invention relates to a kit for use in the present labelling method. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-10340521-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7947513-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005015239-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005054871-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005054871-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005015239-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004111646-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008512644-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-10340521-B4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7799576-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1916527-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7195751-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8679773-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005012247-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8273706-B2 |
| priorityDate |
2001-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |