| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b81f19ece09d5d26b1e493f04c900db4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d01e1266cbba4e1c768097f76a250172
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a82871cd2126b7cfd25f59e9ed692d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b30ebe60632aaeb931c63884a25a3a0a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76de207a62768f061c4e880fd236d2fb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4747 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
2002-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1a1e0b1d8d0f7d41d880f5224b77049
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22174301188109a065e6acf096f8136c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_647ca03724ab22c20f724ffb043220b8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3d55465331466d000627ad89a847115 |
| publicationDate |
2003-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-03054010-A2 |
| titleOfInvention |
Early stage redox-related apoptosis modulator-2 (esram-2) |
| abstract |
The invention provides a polypeptide ESRAM-2 and a nucleic acid encoding said polypeptide. The invention further provides a method for detecting apoptosis in a cell comprising detecting an alteration in any one of: i) an ESRAM-2 polypeptide having an amino acid sequence as set out in SEQ ID NO: 1; ii) a polypeptide having at least 80 % homology with i); iii) a nucleic acid encoding a polypeptide having the sequence set out in i) or ii); iv) a nucleic acid which hybridises under stringent conditions to the sequence set out in iii); or v) the complement of iii) or iv). The invention accordingly provides a method of modulating apoptosis by modulating ESRAM-2 gene expression and a method for identifying genes associated with ESRAM-2 gene expression and thus identifying other genes associated with apoptosis. The invention also provides a novel nucleic acid sequence encoding the promoter region for ESRAM-2. |
| priorityDate |
2001-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |