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publicationDate 2003-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-03053583-A2
titleOfInvention Micro fabricated fountain pen apparatus and method for ultra high density biological arrays
abstract A fluid dispensing system (100) for at least biological applications, e.g., oligonucleotides, peptide nucleic acids ('PNA'), proteins, polysaccharides; polypeptides, inorganic solutions, microelectromechanical systems (MEMS), optical sensors, and other applications. The dispensing system includes a fluid dispensing apparatus for applying selected fluids in a predetermined manner to form a plurality of spots based upon one or more of the selected fluids on a surface of a substrate. The apparatus comprises an elongated member (101) having at least a tip portion (109), which extends from the elongated member. The apparatus also has an etched trench (107) extending along a portion of a length of the elongated member to the tip to form an opening (105) defined on the tip portion and coupled to the etched trench. A flexible region (103) is defined within the elongated member to allow the tip to adjust in position upon contact with the surface of the substrate.
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