| abstract |
A high molecular weight polysaccharide intracellular adhesin (SAE) antigen having the general structure of poly- 1,6,β-2-amidoglucopyranoside, which is variable substituted with N-acetyl and O-succinyl substituents is described. Also, a method is given for isolating this antigen from Staphylococcus aureus. The SAE can be used in a vaccine, either alone, conjugated to an immunogenic protein, and/or with an immunogenic adjuvant. |